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Procedures

McDonald’s cervical cerclage

A cervical cerclage is a surgical procedure in which sutures or synthetic tape is used to reinforce the cervix, and is used in the treatment of cervical incompetence.

McDonald’s cervical cerclage is a type originally described by McDonald in 1957, and is a commonly performed procedure in modern obstetric practice.… Read More “McDonald’s cervical cerclage”

Categories
Pharmacology

Oxytocin: Its Pharmacology and Use in Obstetrics and Gynaecology

Introduction

Oxytocin is one the commonly used drugs in obstetrics and gynaecology as it can be prepared synthetically. It is a peptide hormone secreted by the posterior pituitary gland. It’s also called cuddle or love hormone. It plays an important role in uterine contractions and milk ejection.… Read More “Oxytocin: Its Pharmacology and Use in Obstetrics and Gynaecology”

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Pharmacology

Misoprostol: Its Pharmacology and Use in Obstetrics and Gynaecology

Introduction

Misoprostol is a synthetic prostanglandin E1 analogue commonly used in management of various obstetrics and gynaecology conditions as well as in the management of stomach ulcers.

Its IUPAC nomenclature is Methyl 7-[(1R,2R,3R)-3-hydroxy-2-[(1E)-4-hydroxy-4-methyloct-1-en-1-yl]-5-oxocyclopentyl]heptanoate.

Pharmacokinetics

Misoprostol comes in tablet formulation and can be administered orally, buccally, sublingually, vaginally and rectally.… Read More “Misoprostol: Its Pharmacology and Use in Obstetrics and Gynaecology”