Category: Gynecology

Delayed puberty is defined as the failure of secondary sexual characteristics to appear by the age of 14 years.

Delayed puberty is classified based on the causes into two:

• central (hypogonadotrophic hypogonadism)
• gonadal (hypergonadotrophic hypogonadism).

Central causes of delayed puberty includes conditions that prevent hypothalamic GnRH production/release, such as:

• Constitutional
• Excessive exercise
• Anorexia nervosa
• Kallman’s syndrome
• Pituitary tumour
• Chronic illness (sickle cell disease, diabetes mellitus, etc).

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Precocious puberty is defined as the onset of puberty before the age of 8 years in a girl or 9 years in a boy.

Types of precocious puberty

Precocious puberty is classified based on the causes into two:

• central (also called complete or true)
• peripheral (also called incomplete or pseudo)

Central causes of precocious puberty includes conditions that prematurely activate the hypothalamic GnRH pulsatile release, such as:

1. Cerebral tumours (e.g.

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