Categories
Gynecology

Delayed puberty: Definition, causes and management

Delayed puberty is defined as the failure of secondary sexual characteristics to appear by the age of 14 years.

Delayed puberty is classified based on the causes into two:

  • central (hypogonadotrophic hypogonadism)
  • gonadal (hypergonadotrophic hypogonadism).

Central causes of delayed puberty includes conditions that prevent hypothalamic GnRH production/release, such as:

  • Constitutional
  • Excessive exercise
  • Anorexia nervosa
  • Kallman’s syndrome
  • Pituitary tumour
  • Chronic illness (sickle cell disease, diabetes mellitus, etc).
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Categories
Gynecology

Precocious Puberty: Definition, causes and management

Precocious puberty is defined as the onset of puberty before the age of 8 years in a girl or 9 years in a boy.

Types of precocious puberty

Precocious puberty is classified based on the causes into two:

  • central (also called complete or true)
  • peripheral (also called incomplete or pseudo)

Central causes of precocious puberty includes conditions that prematurely activate the hypothalamic GnRH pulsatile release, such as:

  1. Cerebral tumours (e.g.
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